Search on: RYANODINE RECEPTOR 2 
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Descriptor English:   Ryanodine Receptor Calcium Release Channel 
Descriptor Spanish:   Canal Liberador de Calcio Receptor de Rianodina 
Descriptor Portuguese:   Canal de Liberação de Cálcio do Receptor de Rianodina 
Synonyms English:   Ca Release Channel Ryanodine Receptor
Ca Release Channel-Ryanodine Receptor
Calcium Ryanodine Receptor Complex
Calcium-Ryanodine Receptor Complex
Complex, Calcium-Ryanodine Receptor
Receptor 1, Ryanodine
Receptor 2, Ryanodine
Receptor 3, Ryanodine
Receptor Complex, Calcium-Ryanodine
Receptor, Ryanodine
Receptors, Ryanodine
RyR1
RyR2
RyR3
Ryanodine Receptor
Ryanodine Receptor 1
Ryanodine Receptor 2
Ryanodine Receptor 3
Ryanodine Receptors  
Tree Number:   D12.776.157.530.400.150.800
D12.776.210.500.800
D12.776.543.550.450.150.800
D12.776.543.585.400.150.800
Definition English:   A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES. 
Entry Combination - descr/qualif English:   Ryanodine Receptor Calcium Release Channel/antagonists & inhibitors use Calcium Channel Blockers
Ryanodine Receptor Calcium Release Channel/agonists use Calcium Channel Agonists
 
History Note English:   98; use RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL (NM) 1985-97 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   33489 
Unique Identifier:   D019837 

Occurrence in VHL:
 

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